The SARS-CoV-2 coronavirus infection has shocked the world with the outbreak of a new pandemic that has spread to over 200 countries and infected millions of people. A flu-like condition that can rapidly develop into atypical pneumonia and affect other essential systems, such as the cardiovascular, digestive and immune systems, is its primary manifestation. Some studies have begun relating to conditions that may increase the risk of developing a fatal disease pathway,. Diabetes, hypertension, cardiovascular and coronary disorders, and obesity are included. Such comorbidities present a large inflammatory component that modulates the immune system of the person directly, enhancing its susceptibility to the virus.
Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder focused on the brain that is characterized by lack of social contact, repetitive activities and minimal interests. ASD accounts for a major public health burden, with an estimated annual overall expense of $250 billion in the US, as one of the most common and severe neurodevelopmental disorders. Approximately 1.6% of American children aged 8 years have an ASD and an international prevalence of 0.76% is estimated,. Epidemiology also reports that, with a rate of 3:1 , more patients are men. In recent years, there has been a global trend of increasing the prevalence of ASD, which could be clarified by improvements in diagnostic practice, coding trend, and community-consciousness. However, due to shifts in true risk factors, ASD prevalence may be increased. In addition, data analysis should be vigilant about the increase of frequency in this situation.
ASD (Autism Spectrum Disorder) physiopathology includes many genetic and immune-level changes, such as a rise in inflammatory cytokines and abnormal immune response at many stages. In conditions that are considered a risk factor for symptomatic COVID-19 and its worse outcome, some of these modifications are normal and it is possible to create a correlation between them. Because ASD is a disorder that affects a small, but increasing and articulate portion of the world’s population, and the fact that we do not yet completely understand COVID-19’s entire physiopathology, we would like to bring known evidence with this article that can support the hypothesis that ASD is a risk factor as the other conditions are.
Categories: Mental Health